Studies on the Ethylation of Nucleosides with Triethyloxonium Fluoroborate
- 1 June 1971
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 49 (11) , 1981-1984
- https://doi.org/10.1139/v71-321
Abstract
Alkylation of inosine and adenosine triacetates with triethyloxonium fluoroborate leads to selective N-ethylation. Inosine triacetate affords 7-ethylinosine as a major product, while adenosine triacetate is ethylated at the N-6 and -1 positions. Treatment with base affords the 6-ethyl analog by rearrangement.Keywords
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