VERAPAMIL AS A HYPOTENSIVE AGENT DURING NEUROLEPTANAE STHE S IA
Open Access
- 1 August 1981
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 53 (8) , 885-889
- https://doi.org/10.1093/bja/53.8.885
Abstract
The haemodynamic effects of verapaniil were investigated in 11 patients anaesthetized with thiopentone, fentanyl and dehydrobenzperidol. Suxamethonjpm and pancuronium bromide were used for muscle relaxation. Verapamil 0.07 mg–1 given as a single intravenous bolus decreased mean arterial pressure from 108±18mm Hg to 84±2OmmHg (P–1 (P<0.001) while heart rate and mean pulmonary artery pressure showed only minor changes. The decrease in arterial presstir was caused by reduction in total peripheral resistance while cardiac output was increased.Keywords
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