In Vitro Activities of New Quinolones and Oxazolidinones against Actinomadura madurae
- 1 March 2004
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (3) , 1037-1039
- https://doi.org/10.1128/aac.48.3.1037-1039.2004
Abstract
In this work, we studied the in vitro sensitivity of 24 strains of Actinomadura madurae to a new oxazolidinone (DA-7867), gatifloxacin, moxifloxacin, and garenoxacin by using a broth microdilution method. We observed that the A. madurae strains had a high level of sensitivity to all the antimicrobials tested. The most active drug was DA-7867, with a MIC at which 90% of the strains are inhibited (MIC 90 ) of 0.125 μg/ml and a MIC 50 of 0.06 μg/ml.Keywords
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