Isolation and Hypoglycemic Activity of Atractans A, B and C, Glycans ofAtractylodes japonicaRhizomes1

Abstract
A water extract of the Oriental crude drug “byaku-jutsu”, Atractylodes japonica rhizomes, showed hypoglycemic activity in mice. The extract was fractionated by monitoring the pharmacological activity to obtain three glycans, atractans A, B and C. These constituents exerted significant hypoglycemic actions in normal and alloxan-induced hyperglycemic mice.

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