Identification of a glutathione peroxidase homolog inNeisseria meningitidis
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis in DNA Sequence
- Vol. 6 (1) , 55-60
- https://doi.org/10.3109/10425179509074701
Abstract
Glutathione peroxidase is an antioxidant enzyme found in a diverse array of eukaryotic species. We have determined the DNA sequence of a glutathione peroxidase homolog in the pathogenic bacterium Neisseria meningitidis. The sequence displays features of a functional gene, but lacks a selenocysteine-encoding in-frame TGA codon characteristic of most mammalian glutathione peroxidase genes. The derived amino acid sequence encoded by the N. meningitidis homolog predicts a 19.9 kDa protein that displays a high level of amino acid identity with other gluathione peroxidase sequences, particularly within four conserved regions of the enzyme.Keywords
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