Murine mammary FM3A carcinoma cells transformed with the herpes simplex virus type 1 thymidine kinase gene are highly sensitive to the growth‐inhibitory properties of (E)‐5‐(2‐bromovinyl)‐2'‐deoxyuridine and related compounds
Open Access
- 3 June 1985
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 185 (1) , 95-100
- https://doi.org/10.1016/0014-5793(85)80747-x
Abstract
Murine mammary carcinoma (FM3A TK−/HSV‐1 TK+) cells, which are thymidine kinase (TK)‐deficient but have been transformed with the herpes simplex virus type 1 (HSV‐1) TK gene are inhibited in their gr...Keywords
This publication has 28 references indexed in Scilit:
- Biochemical aspects of the selective antiherpes activity of nucleoside analoguesBiochemical Pharmacology, 1984
- 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication.Proceedings of the National Academy of Sciences, 1983
- Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanineAntimicrobial Agents and Chemotherapy, 1983
- Nucleosides. 123. Synthesis of antiviral nucleosides: 5-substituted 1-(2-deoxy-2-halogeno-.beta.-D-arabinofuranosyl)cytosines and -uracils. Some structure-activity relationshipsJournal of Medicinal Chemistry, 1983
- A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2Antimicrobial Agents and Chemotherapy, 1982
- Antiherpesviral and anticellular effects of 1-beta-D-arabinofuranosyl-E-5-(2-halogenovinyl) uracilsAntimicrobial Agents and Chemotherapy, 1981
- 2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agentAntimicrobial Agents and Chemotherapy, 1980
- (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.Proceedings of the National Academy of Sciences, 1979
- Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosidesJournal of Medicinal Chemistry, 1979
- Trisodium Phosphonoformate, a New Antiviral CompoundScience, 1978