Disease concordance and sex similarity in twins
- 1 March 1980
- journal article
- research article
- Published by BMJ in Journal of Epidemiology and Community Health
- Vol. 34 (1) , 1-8
- https://doi.org/10.1136/jech.34.1.1
Abstract
The limitations of the Weinberg rule and of concordance estimates in relation to simple genetic models of [human] disease are discussed. A general analytical framework which largely circumvents these problems and allows causal inferences from twin data is advanced. The new model was tested using published data on mongolism, schizophrenia, coronary occlusion, congenital neural tube defects and infantile hypertrophic pyloric stenosis.This publication has 12 references indexed in Scilit:
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