Recreational Physical Activity and Breast Cancer Risk among Women under Age 45 Years
Open Access
- 1 February 1998
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Epidemiology
- Vol. 147 (3) , 273-280
- https://doi.org/10.1093/oxfordjournals.aje.a009447
Abstract
To evaluate whether recreational physical activity is associated with breast cancer among young women, the authors analyzed data from a population-based case-control study. Cases (n = 1, 668) were women under age 45 years who had been newly diagnosed with breast cancer between 1990 and 1992 in Atlanta, Georgia, central New Jersey, or Seattle, Washington. Controls (n = 1, 505) were frequency-matched to cases by 5-year age group and geographic area of residence. Breast cancer was not associated with recreational activity in any of the three time periods assessed (highest quartile of activity vs. lowest: age- and center-adjusted odds ratio (OR) = 0.94 (95% confidence interval (Cl) 0.77–1.15) at ages 12–13 years, OR = 1.08 (95% Cl 0.88–1.32) at age 20 years, and OR = 1.18 (95% Cl 0.97–1.44) during the past year), with the average of the three time periods (OR = 1.02, 95% Cl 0.84–1.25), or with daily climbing of at least two flights of stairs (without stopping) during the past year (daily climbing vs. never climbing: OR = 1.03, 95% Cl 0.86–1.23). Estimates were not modified or confounded by body mass index, menopausal status, or caloric intake during the past year. These results do not support a protective role for physical activity in the risk of breast cancer among young women. Am J Epidemiol 1998; 147: 273–80.Keywords
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