A placebo controlled evaluation of lomefloxacin in the treatment of bacterial diarrhoea in the community
- 1 July 1995
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 36 (1) , 259-263
- https://doi.org/10.1093/jac/36.1.259
Abstract
We compared 40 patients taking lomefloxacin 400 mg once daily for 5 days in a double blind trial with 44 placebo takerswith proven community acquired bacterial diarrhoea (85% due to Campylobacter spp.)- Lomefloxacin eradicated Campylobacter spp. in 75% but did not alter clinical outcome. Twenty-eight per cent of the campylobacter isolates developed resistance. Thirty-three per cent developed side-effects. Lomefloxacin is not recommended for community-acquired bacterial diarrhoea when Campylobacter spp. predominate.Keywords
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