Field approach to three-dimensional gene expression pattern characterization
- 31 March 2005
- journal article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 86 (14)
- https://doi.org/10.1063/1.1898424
Abstract
We present a vector field method for obtaining the spatial organization of 3D patterns of gene expression based on gradients and lines of force obtained by numerical integration. The convergence of these lines of force in local maxima are centers of gene expression, providing a natural and powerful framework to characterize the organization and dynamics of biological structures. We apply this novel methodology to analyze the expression pattern of the Enhanced Green Fluorescent Protein (EGFP) driven by the promoter of light chain myosin II during zebrafish heart formation.Comment: 9 pages, 2 figures, The following article has been submitted to Applied Physics Letters. If it is published, it will be found online at http://apl.aip.orKeywords
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