Standardization and Efficacy of Allergen Extracts
- 18 November 1976
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 295 (21) , 1195-1196
- https://doi.org/10.1056/nejm197611182952113
Abstract
The paper by Metzger et al. in this issue of the Journal is an excellent example of the continuing research aimed at improving the immunotherapy of allergic disorders and better understanding of the mechanisms whereby favorable clinical results occur. This work follows a series of efforts, dating from the 1930′s, to modify allergenic materials so that they may be administered more safely. More recently, these efforts have also been directed to preserving or enhancing the capacity of allergenic extracts to produce an IgG (blocking) antibody response, a measure of immunogenicity correlated with clinical efficacy. Metzger et al. report that increasing . . .Keywords
This publication has 3 references indexed in Scilit:
- Allergens and the Genetics of AllergyPublished by Elsevier ,1975
- Measurement of the potency of allergy extracts by their inhibitory capacities in the radioallergosorbent testJournal of Allergy and Clinical Immunology, 1974
- The potency and antigen E content of commercially prepared ragweed extractsJournal of Allergy, 1970