Lymphocyte-Derived Progesterone-Induced Blocking Factor Corrects Resorption in a Murine Abortion System
- 9 May 1990
- journal article
- research article
- Published by Wiley in American Journal of Reproductive Immunology
- Vol. 23 (1) , 26-28
- https://doi.org/10.1111/j.1600-0897.1990.tb00664.x
Abstract
An anti-abortive effect of a progesterone-induced blocking factor has been shown in the CBA/J.times.DBA/2 abortion system. I.p. injections of pregnant mice on days 7.5, 9.5, and 11.5 of gestation with dialyzed supernatants from progesterone-treated murine pregnancy spleen cells (but not from control ones) significantly (P<0.01) reduced the resorption rate from 47.7% in the untreated animals to 20.7%.Keywords
This publication has 11 references indexed in Scilit:
- Reactivity of lymphocytes to a progesterone receptor-specific monoclonal antibodyCellular Immunology, 1990
- Lymphocytic progesterone receptors in normal and pathological human pregnancyJournal of Reproductive Immunology, 1989
- ELISA test for the detection of an immunological blocking factor in human pregnancy serumJournal of Reproductive Immunology, 1989
- Immunoregulatory effects of a suppressor factor from healthy pregnant women's lymphocytes after progesterone inductionCellular Immunology, 1989
- Complete freund adjuvant reverses high fetal resorption rate in CBA/JX DBA/2J mouse combinationJournal of Reproductive Immunology, 1989
- Immunological and para-immunological mechanisms in spontaneous abortion: recent insights and future directionsJournal of Reproductive Immunology, 1987
- Characterization of hormone-dependent suppressor cells in the uterus of mated and pseudopregnant miceJournal of Reproductive Immunology, 1987
- The Mechanism of the Inhibitory Effect of Progesterone on Lymphocyte Cytotoxicity: I. Progesterone‐Treated Lymphocytes Release a Substance Inhibiting Cytotoxicity and Prostaglandin SynthesisAmerican Journal of Reproductive Immunology, 1985
- Preferential elimination of NK and CTL functions by anti-D44 monoclonal antibody.The Journal of Immunology, 1984
- Regulatory T cells in pregnancy. IV. Genetic characteristics and mode of action of early MLR suppressive T cell subpopulations.The Journal of Immunology, 1981