Serum and liver radioactivity levels in mice after intraperitoneal and subcutaneous injection of [14C]orotic acid
- 1 March 1977
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 33 (3) , 302-304
- https://doi.org/10.1007/bf02002792
Abstract
[14C]Orotic acid was rapidly distributed in blood after, both i.p. and s.c. injection but was not completely absorbed from the peritoneal cavity until 20 min after injection. S.c. injection should be an acceptable alternative to i.p. injection although the incorporation into the liver acid soluble- and RNA-fractions was somewhat delayed after the s.c. injection.Keywords
This publication has 10 references indexed in Scilit:
- Factors influencing the serum activity in mice after intravenous and intraperitoneal injection of14C orotic acidCellular and Molecular Life Sciences, 1975
- Imcorporation of Orotic Acid into Nucteotides and RNA in Mouse Organs during 60 MinutesHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1975
- Clearance of concentrated thymidine and deoxycytidine from the plasma of CBA miceCellular and Molecular Life Sciences, 1974
- A mouse bleeding technic yielding consistent volume with minimal hemolysis.1973
- The problem of tissue sampling from experimental animals with respect to freezing technique, anoxia, stress and narcosisArchives of Biochemistry and Biophysics, 1972
- Nucleotide pools and [6-14C]orotic acid incorporation in early regenerating rat liverBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966
- Recent developments in the measurement of nucleic acids in biological materials. A supplementary reviewThe Analyst, 1966
- Distribution of Tritiated Thymidine in Various TissuesNature, 1965
- NUCLEOTIDE METABOLISMPublished by Elsevier ,1954
- NUCLEOTIDE METABOLISM .1. THE CONVERSION OF OROTIC ACID-6-C-14 TO URIDINE NUCLEOTIDES1954