Rosette-Forming Lymphocytes in Hodgkin’s Disease
- 18 October 1973
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 289 (16) , 863
- https://doi.org/10.1056/nejm197310182891615
Abstract
To the Editor: The ability of lymphocytes to form spontaneous rosettes with sheep red blood cells (SRBC) in vitro can be used as a marker for human thymus-dependent (T) lymphocytes.1 2 3 Wybran et al. (N Engl J Med 288:710–713, 1973) reported that the percentage of this lymphocyte population wras diminished in patients with defective cellular immunity, whereas patients with humoral immune deficiency had normal numbers of T cells.Since impairment in delayed hypersensitivity may occur in Hodgkin's disease,4 , 5 we determined the number of blood lymphocytes forming SRBC rosettes2 , 3 in 10 patients with various stages of the disease. The number of lymphocytes . . .Keywords
This publication has 7 references indexed in Scilit:
- Human lymphocyte-sheep erythrocyte rosette formation: Some characteristics of the interationClinical Immunology and Immunopathology, 1973
- Thymus-Derived Rosette-Forming Cells in Various Human Disease States: Cancer, Lymphoma, Bacterial and Viral Infections, and Other DiseasesJournal of Clinical Investigation, 1973
- Studies of T- and B-Lymphocytes in Patients with Connective Tissue DiseasesJournal of Clinical Investigation, 1973
- SURFACE MARKERS ON HUMAN T AND B LYMPHOCYTESThe Journal of Experimental Medicine, 1972
- Binding of Sheep Erythrocytes to Human LymphocytesScandinavian Journal of Immunology, 1972
- Delayed hypersensitivity in Hodgkin's diseaseThe American Journal of Medicine, 1972
- IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTESThe Journal of Experimental Medicine, 1971