THE EFFECT OF THE DINOSEB-ACETATE (ARETIT) HERBICIDE ON THE ACTIVITIES OF TRANSAMINASES (GOT, GPT) IN THE BLOOD-SERUM AND MUSCLE OF JAPANESE QUAIL (COTURNIX-COTURNIX JAPONICA)

  • 1 January 1980
    • journal article
    • research article
    • Vol. 25  (11) , 697-702
Abstract
Effect of dinoseb-acetate (Aretit) herbicide, administered in drinking water at a concentration of 100 and 200 mg/l for 4 days on activity of transaminases (GOT [glutamic oxaloacetic transminase] and GPT [glutamic pyruvic transaminase]) in blood serum and muscle of Japanese quail (C. coturnix japonica) was studied. GOT had higher activity values in blood serum and muscle of control and test birds. The herbicide increased GOT activity in blood serum but GPT remained unchanged. In muscle, activity of GOT decreased as a result of action of dinoseb-acetate and GPT activity remained unchanged. Under in vitro conditions, dinoseb-acetate (concentrated 0.01-1000 mg/l) increased GOT activity in blood serum and muscle; GPT activity remained the same. Transaminases were specifically involved in the adaptation mechanisms of animals to dinoseb-acetate intoxication.

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