THE PRODUCTION OF IMMUNO-CONGLUTININ: I. FACTORS AFFECTING THE RESPONSE OF MICE TO HETEROSTIMULATION

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Abstract
Mice are capable of producing immuno-conglutinin in response to hetero-stimulation. This species was used to test a number of preparations of bacteria and kaolin for their ability to stimulate immuno-conglutinin production. It was found that complement activity must be present in the serum used to alexinate the bacteria or active particles in order to produce a significant immuno-conglutinin response. The available evidence indicates that adsorbed complement is the specific stimulus for the production of immuno-conglutinin.