CELL MEMBRANE ALLOANTIGENIC DETERMINANTS OF SEVERAL UNUSUAL MOUSE STRAINS

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Abstract
The lymphocytes of several interesting and clinically important strains of Mus musculus were serotyped with alloantisera recognizing the different alleles of the Thy-1, Ly-1, Ly-2, Ly-3, Ly-4, Ly-5, Ly-6 and Ly-7 loci. The strains were the Biozzi high and low responder strains, of importance in immune responsiveness studies, and the strains BXSB, MRL and MRL.sbd.lpr/lpr.sbd.strains which spontaneously develop immune complex disease. The related species M. musculus castaneus was also typed with the same reagents. The knowledge of the cell surface phenotype should prove useful in various functional studies involving these interesting strains.