The Trypanocidal Effect of Nucleocidin In vivo
- 1 June 1957
- journal article
- research article
- Published by JSTOR in Journal of Parasitology
- Vol. 43 (3) , 291-293
- https://doi.org/10.2307/3274350
Abstract
A new antibiotic, nucleocidin, was tested for trypanocidal activity against Trypanosoma congolense, T. equinum, and T. gambiense. Three daily doses totaling 0.15 mg/kg produced approximately 95% cures in rats and mice infected with T. congolense, 91% in mice infected with T. equinum, and 73% in mice infected with T. gambiense. This is the first report of an antibiotic highly active against T. congolense.Keywords
This publication has 3 references indexed in Scilit:
- Influence of the Amino Nucleoside of Puromycin on the Course and Pathology of Trypanosome Infections in Rabbits and MiceThe American Journal of Tropical Medicine and Hygiene, 1956
- The Effect of Puromycin on Six Species of Trypanosoma in MiceThe American Journal of Tropical Medicine and Hygiene, 1954
- The Effects of Erythromycin (Ilotycin, Lilly) against Certain Parasitic OrganismsThe American Journal of Tropical Medicine and Hygiene, 1953