Digital subtraction of eye movement artefact from pattern ERG recordings

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Abstract
The electroretinal response to phase-alternating spatial patterns, the pattern electroretinogram (PERG). appears to originate in and reflect function of the ganglion cell layer of the retina. Consequently, PERG recording may have utility for the evaluation of central disorders of vision in Neuro-Ophthalmology. Many neurological patients have uncontrollable eye movements in the form of nystagmus, which is often enhanced by viewing the phase-alternating stimulus used to elicit the PERG, thereby producing gross eye movement and electrode movement artefacts. A technique is described for the elimination of electrode movement artefact and for the digital subtraction of averaged eye movement artefact from the contaminated PERG recordings, thereby deriving a purer PERG tracing.

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