Mononuclear Leucocyte Chemotaxis in Boyden Chambers: Inhibition by Subantimitotic Concentrations of Antitubulins
- 1 March 1978
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 7 (3) , 233-238
- https://doi.org/10.1111/j.1365-3083.1978.tb00449.x
Abstract
The chemotaxis of Lymphoprep-isolated human mononuclear leukocytes (L-MNs) from peripheral blood was inhibited by subantimitotic concentrations of the antitubulins demecolcine, podophyllic acid ethylhydrazide, vinblastine and griseofulvin. L-MN chemotaxis, like polymorphonuclear leukocyte (PMN) chemotaxis, is probably composed of a direct antitubulin-insensitive chemotaxis and a leukocyte-induced antitubulin-sensitive chemotaxis.This publication has 6 references indexed in Scilit:
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