LYMPHOCYTIC LEUKEMIA: AN ANALYSIS OF FREQUENCY, DISTRIBUTION AND MORTALITY AT THE UNIVERSITY OF CALIFORNIA HOSPITAL, 1913-1947

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Abstract
Statistics are presented regarding the age of onset, sex, duration of illness, and mortality of 149 patients with acute lymphocytic leukemia and 137 patients with chronic lymphocytic leukemia seen at the U. of Calif. Hosp., 1913 to 1947, inclusive. The data are compared with 16 similar reports in the literature, 8 on acute leukemia and 8 on chronic leukemia. Age and sex distr. and duration of illness in acute lymphocytic leukemia remained fairly constant during the period of study. There may have been a shift toward a higher age at onset among patients with chronic lymphocytic leukemia, but the sex distr. and duration of illness remained fairly constant. The mean duration of illness from onset to death in 149 cases of acute lymphocytic leukemia was found to be 5.4 mos. The duration of illness was longer among the age group 5-14 yrs. than in age groups 0-4 yrs. and 14 yrs. and over, and was longer in patients with initially low, than in those with high, leukocyte counts. The mean duration of illness from onset to death in 137 cases of chronic lymphocytic leukemia was 42 mos. No differences were present relative to age at onset or the initial leukocyte count.