Hemoglobin Baylor [α2β281(EF5) Leu→ arc]-an Unstable Mutant with High Oxygen Affinity
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in Hemoglobin
- Vol. 1 (1) , 85-96
- https://doi.org/10.3109/03630267609031024
Abstract
The amino acid substitution in a new homoglobin variant, Hb Baylor [α2β281(EF5) Leu-Arg], has been determined by application of column chromatography and amino acid analysis of the tryptic peptides. The hemoglobin is somewhat unstable and it has a high oxygen affinity. The porosities shows the opposing hematologic effects of these two properties-the instituionability being associated with increased destruction, and the high O2 affinity with increased production, of erythrocytes.Keywords
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