A Plant miRNA Contributes to Antibacterial Resistance by Repressing Auxin Signaling
Top Cited Papers
- 21 April 2006
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 312 (5772) , 436-439
- https://doi.org/10.1126/science.1126088
Abstract
Plants and animals activate defenses after perceiving pathogen-associated molecular patterns (PAMPs) such as bacterial flagellin. In Arabidopsis , perception of flagellin increases resistance to the bacterium Pseudomonas syringae , although the molecular mechanisms involved remain elusive. Here, we show that a flagellin-derived peptide induces a plant microRNA (miRNA) that negatively regulates messenger RNAs for the F-box auxin receptors TIR1, AFB2, and AFB3. Repression of auxin signaling restricts P. syringae growth, implicating auxin in disease susceptibility and miRNA-mediated suppression of auxin signaling in resistance.Keywords
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