Modulation of the tumor vasculature functionality by ionizing radiation accounts for tumor radiosensitization and promotes gene delivery
Open Access
- 18 October 2002
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 16 (14) , 1979-1981
- https://doi.org/10.1096/fj.02-0487fje
Abstract
The ultimate goal of radiotherapy is to induce irreversible damages in genetically unstable, fast-growing cancer cells while minimizing the cytotoxic effects on host tissues. The satus of the tumor v...Keywords
This publication has 26 references indexed in Scilit:
- Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapyNature Medicine, 2001
- Angiogenesis Research: Guidelines for Translation to Clinical ApplicationThrombosis and Haemostasis, 2001
- Changes in tumor hypoxia measured with a double hypoxic marker techniqueInternational Journal of Radiation Oncology*Biology*Physics, 2000
- Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant StressCirculation Research, 2000
- Tumor angiogenesis: past, present and the near futureCarcinogenesis: Integrative Cancer Research, 2000
- Transcriptional and Posttranscriptional Regulation of Endothelial Nitric Oxide Synthase Expression by Hydrogen PeroxideCirculation Research, 2000
- Modification of tumor blood flow: Current status and future directionsSeminars in Radiation Oncology, 1998
- Vasculature and microenvironmental gradients: the missing links in novel approaches to cancer therapy?Advances in Enzyme Regulation, 1998
- Antiangiogenic therapy of experimental cancer does not induce acquired drug resistanceNature, 1997
- Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumoursNature, 1996