OCCURRENCE OF ORNITHINE δ-TRANSAMINASE: A DICHOTOMY
- 15 September 1957
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 43 (9) , 796-803
- https://doi.org/10.1073/pnas.43.9.796
Abstract
Instances of "biochemical diversity" have held a persistent attraction for students of biochemistry and physiology and of taxonomy and evolution. The difference in ornithine synthesis and the concomitant difference in ornithine [alpha]-transaminase activity between Neurospora crassa and Escherichia coli, prompted an investigation of the occurrence of this activity among various organisms. The transaminase activity was not detected in extracts of any of the gram-negative bacteria or of the blue-green alga tested, but was uniformly found in extracts of the gram-positive bacteria, fungi, non-blue-green algae, theprotozoon, and the higher plant and animal tissues examined. Thus, in harmony with available information, the group containing the gram-negative bacteria and blue-green algae appears to be set apart from other organisms. The distribution pattern found is particularly interesting in comparison with the known distribution pattern of [alpha],[reverse arrow][long dash] diaminopimelic acid. The two patterns may well reflect two similar, but not identical, dichotomies in the biological world. A group of certain gram-positive bacteria are intermediate forms in that they occupy a region between the two points of division indicated by the two distribution patterns.This publication has 29 references indexed in Scilit:
- N-succinyl-L-diaminopimelic acid, an intermediate in the biosynthesis of diaminopimelic acidBiochimica et Biophysica Acta, 1957
- Biochemistry of the Bacterial Cell WallNature, 1957
- Nature and Site of Origin of the Hyperglycæmic Substance released following an Injection of Growth HormoneNature, 1957
- On the glutamic family and lysine in Neurospora: enzymic formation of glutamic γ-semialdehyde and α-aminoadipic σ-semialdehyde from penta- and hexahomoserineBiochimica et Biophysica Acta, 1957
- The Chemical Composition of the Cell Wall in some Gram-positive Bacteria and its Possible Value as a Taxonomic CharacterJournal of General Microbiology, 1956
- Nécessité des orthodiphénols pour la croissance de coccus P (Sarcina sp.)Biochimica et Biophysica Acta, 1956
- The Gram Reaction and Cell Composition: Nucleic Acids and other Phosphate fractionsJournal of General Microbiology, 1954
- The Distribution of , -Diaminopimelic Acid among various Micro-organismsJournal of General Microbiology, 1953
- The relationships in biosynthesis of the β-galactosidase- and Pz-proteins in Escherichia coliBiochimica et Biophysica Acta, 1953
- On ornithine and proline synthesis in Escherichia coliBiochimica et Biophysica Acta, 1953