A Convenient, Large-Scale Preparation of a Differentially Protected α-Aminoglycine Suitable for the Synthesis of α-Aminoglycine-Containing Peptides
- 1 September 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (17) , 3237-3239
- https://doi.org/10.1080/00397919608004632
Abstract
α-Boc-amino-Fmoc-glycine 6 was prepared in two steps from 9-fluorenyl-methylcarbamate 1, glyoxylic acid 3 and t-butyl carbamate 5. This compound is useful in Solid Phase Peptide Synthesis to prepare α-aminoglycine-containing peptides using Fmoc-strategy.Keywords
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