The Virulence to Man of Japanese Encephalitis Virus in Thailand

Abstract
A total of nine cases of serologically confirmed Japanese encephalitis occurred in five units of U. S. Marines stationed in Thailand in July and August 1972, and 27% of 2,101 Marines in these units had evidence of recent JEV infection. The apparent-to-inapparent infection ratio of 1:63 in this epidemic is higher than that previously described in Asians, but similar to that previously estimated in U. S. troops in Korea. This study confirms the human virulence of Japanese encephalitis virus in Thailand and provides strong evidence that Thai strains are of similar human virulence to strains infecting Americans in more northern latitudes in earlier studies.

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