Generation of a Reporter Cell Line for Detection of Infectious Varicella-Zoster Virus and Its Application to Antiviral Studies
- 1 September 2006
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 50 (9) , 3142-3145
- https://doi.org/10.1128/aac.00342-06
Abstract
To simplify the titration of infectious varicella-zoster virus (VZV), we generated a reporter cell line that produced luciferase in a dose-dependent manner upon infection with cell-free VZV. A few VZV-infected cells were detectable by coculturing with the cell line. We demonstrated the usefulness of the cell line for antiviral studies.Keywords
This publication has 33 references indexed in Scilit:
- Transcriptomal analysis of varicella-zoster virus infection using long oligonucleotide-based microarraysJournal of General Virology, 2005
- 4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as Non-Nucleoside Inhibitors of Human Cytomegalovirus and Related Herpesvirus PolymerasesJournal of Medicinal Chemistry, 2005
- Comparison of serologic responses between Kaposi's sarcoma‐positive and ‐negative men who were seropositive for both human herpesvirus 8 and human immunodeficiency virusJournal of Medical Virology, 2004
- Inhibition of Infection and Replication of Human Herpesvirus 8 in Microvascular Endothelial Cells by Alpha Interferon and Phosphonoformic AcidJournal of Virology, 2004
- Array Analysis of Viral Gene Transcription during Lytic Infection of Cells in Tissue Culture with Varicella-Zoster VirusJournal of Virology, 2003
- Current Pharmacological Approaches to the Therapy of Varicella Zoster Virus InfectionsDrugs, 1999
- Anatomy of the Varicella‐Zoster Virus Open‐Reading Frame 4 PromoterThe Journal of Infectious Diseases, 1998
- Improved detection of varicella zoster infection with a spin amplification shell vial technique and blind passageClinical and Diagnostic Virology, 1996
- Frequent isolation of human herpesvirus 7 from salivaVirus Research, 1993
- The Complete DNA Sequence of Varicella-Zoster VirusJournal of General Virology, 1986