PIGMENTARY DISTURBANCE FOLLOWING EXPOSURE TO MONOBENZYL ETHER OF HYDROQUINONE

Abstract
In 1940, Schwartz, Oliver and Warren1 reported the presence of depigmentation secondary to the wearing of yellow rubber gloves. The etiologic factor responsible for the leukoderma was traced to monobenzyl ether of hydroquinone (agerite alba®), an antioxidant used in the preparation of the rubber. After the original report, Schwartz,2 in 1947, recorded several additional cases. The purpose of this communication is to report further instances of this cosmetic disorder, including new data, to record the first case known to us in which hyperpigmentation resulted, to emphasize the probability that this dermatosis is more frequently encountered than the literature implies and to stress the fact that this disorder is not solely occupational in origin. Considering the diversified and numerous rubber products previously treated with monobenzyl ether of hydroquinone, the determination of the origin of this pigmentary disorder often might prove difficult or impossible. The reports in this paper include