REARRANGEMENT OF CHROMOSOME 21 IN ALZHEIMERS-DISEASE
- 1 January 1986
- journal article
- research article
- Vol. 29 (4) , 226-228
Abstract
We have analyzed the DNA from four patients suffering from a dementia of the Alzheimer type and of four controls of identical age. Estimates of the copy numbers of two genes located on chromosome 21, SOD1 and ETS2, gave the following results: in all the cases there was duplication of ETS2 whereas SOD1 was normal. These preliminary results indicate that the segment of chromosome 21(q21 .fwdarw. q22.1) is rearranged in all the four patients who were investigated.This publication has 5 references indexed in Scilit:
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