The changing prevalence of secondary cardiac neoplasms as related to cancer therapy

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Abstract
A 25-year-review of 1303 autopsies with metastatic non-reticuloendothelial and non-central nervous system malignancies revealed secondary cardiac neoplasms in 179 cases (14%). When the autopsies were divided into two groups by time period, a significant increased prevalence of secondary cardiac neoplasms was demonstrated during the later period (1966–1977). This noted increase was not influenced by chemotherapy but was apparently related to attempted curative surgical and/or radiation therapy.