Mitochondrial Genetics in Bakers' Yeast: A Molecular Mechanism for Recombinational Polarity and Suppressiveness
- 1 November 1974
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 71 (11) , 4612-4616
- https://doi.org/10.1073/pnas.71.11.4612
Abstract
Recombinational polarity and suppressiveness are two well-known but puzzling cytoplasmic genetic phenomena in bakers' yeast, Saccharomyces cerevisiae . Little progress has been made in characterizing the underlying molecular mechanisms of these phenomena. In this paper we describe a molecular model for recombinational polarity that is compatible with the available genetic evidence. The model stresses the role of small deletions and excision/repair processes in otherwise canonical recombinational events. According to the model, both phenomena require recombination and may share mechanistic elements.This publication has 31 references indexed in Scilit:
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