Tn4001: A gentamicin and kanamycin resistance transposon in Staphylococcus aureus
- 1 March 1984
- journal article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 193 (3) , 554-556
- https://doi.org/10.1007/bf00382099
Abstract
We describe a 4.5 kilobase transposon. Tn4001, which mediates resistance to gentamicin, tobramycin and kanamycin in Staphylococcus aureus. Originally detected in plasmid pSK1, Tn4001 was shown to undergo rec-independent transposition to the chromosome from this plasmid and from an inserted derivative of the plasmid pII147. Heteroduplexes between plasmids with and without Tn4001 demonstrated a characteristic stem and loop structure with inverted repeats of approx. 1.3 kilobases.Keywords
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