The prognostic and therapeutic implications of the positive radionuclide bone scan in clinically early breast cancer
- 1 September 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 65 (9) , 649-652
- https://doi.org/10.1002/bjs.1800650918
Abstract
Seventy-five women with clinical stage I or stage II carcinoma of the breast have had radionuclide bone scans at the time of presentation and at 6-monthly intervals during a mean follow-up period of 39 months. Patients with evidence of metastases on bone scan, either at the time of presentation or during follow-up, had significantly higher mortality and morbidity rates than those with persistently negative scans. Whatever the clinical stage, breast cancer patients with a positive bone scan have a very poor short term prognosis and local therapy to the breast is inadequate. A plan is outlined which incorporates the patient's bone scan status into the decision to introduce endocrine therapy or chemotherapy.Keywords
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