Rational design of selective thrombin inhibitors
- 1 January 1997
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 7 (7) , 769-774
- https://doi.org/10.1016/s0960-894x(97)00115-7
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Challenges in the development of orally bioavailable thrombin active site inhibitorsBlood Coagulation & Fibrinolysis, 1995
- Synthesis of Thrombin Inhibitor DuP 714The Journal of Organic Chemistry, 1995
- Design and Synthesis of Potent and Highly Selective Thrombin InhibitorsJournal of Medicinal Chemistry, 1994
- Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profileTrends in Pharmacological Sciences, 1993
- In Vivo Anticoagulant and Antiplatelet Effect of D-Phe-Pro-Arg-H and D-MePhe-Pro-Arg-HThrombosis and Haemostasis, 1992
- Thrombin structure and functionBlood Coagulation & Fibrinolysis, 1991
- Comparative modeling methods: Application to the family of the mammalian serine proteasesProteins-Structure Function and Bioinformatics, 1990
- X-Ray Analysis of a Thrombin Inhibitor-Trypsin Complex1The Journal of Biochemistry, 1989
- ThrombinaAnnals of the New York Academy of Sciences, 1986
- Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperidinecarboxylic acidBiochemistry, 1984