The Hamilton Rating Scale. An Assessment Based on a Dothiepin (‘Prothiaden’) versus Imipramine (‘Tofranil’) Clinical Trial

Abstract
The Hamilton Rating Scale for Depression is in common use, particularly in durg trials. The authors compared this scale with a system of psychiatric assessment and recording designed by M. Sim. They found that there was closer agreement with the full assessment of the Sim method than with the single diagnostic area for depression. This suggests that the Hamilton Scale for depression is more general than specific in its application.

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