Transcripts of human HLA gene fragments lacking the 5'-terminal region in transfected mouse cells.
- 1 February 1984
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 81 (3) , 649-653
- https://doi.org/10.1073/pnas.81.3.649
Abstract
Clones of mouse L cells transfected with a human HLA-B7 gene fragment lacking the 5'' segment of exon 2 and all upstream sequences express HLA-specific transcripts of various lengths. These include species that correspond in size to full-length HLA-B7 mRNA. The level of these transcripts is increased in cells treated with interferon. The full-length transcripts probably raise as a result of the linkage of the HLA-B7 gene fragments with DNA segments providing transcription initiation or polyadenylylation signals.Keywords
This publication has 23 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- Selective extraction of polyoma DNA from infected mouse cell culturesPublished by Elsevier ,2004
- Controlled transcription of a human α-interferon gene introduced into mouse L cellsNature, 1982
- The making of strand-specific M13 probesGene, 1982
- Major histocompatibility antigens: The human (HLA-A,-B,-C) and murine (H-2K, H-2D) class I moleculesCell, 1981
- The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAsCell, 1981
- Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virusGene, 1979
- Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysisCell, 1978
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Sequence at the 3′ end of globin mRNA shows homology with immunoglobulin light chain mRNANature, 1974