Trans- and cis-DNA adduct concentration in epidermis from mouse and rat skin treated ex vivo with benzo[a]pyrene diol epoxide and its corresponding chlorohydrin
- 8 June 2001
- journal article
- Published by Elsevier in Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
- Vol. 478 (1-2) , 199-206
- https://doi.org/10.1016/s0027-5107(01)00153-1
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Synthesis and Characterization of Bay Region Halohydrins Derived from Benzo[a]pyrene Diol Epoxide and Their Role as Intermediates in Halide-Catalyzed Cis Adduct FormationChemical Research in Toxicology, 1998
- Mutagenic Potential of Stereoisomeric Bay Region (+)- and (−)-cis-anti-Benzo[a]pyrene Diol Epoxide-N2-2‘-deoxyguanosine Adducts in Escherichia coli and Simian Kidney CellsBiochemistry, 1998
- Sequence Context Profoundly Influences the Mutagenic Potency of Trans-Opened Benzo[a]pyrene 7,8-Diol 9,10-Epoxide−Purine Nucleoside Adducts in Site-Specific Mutation StudiesBiochemistry, 1998
- Benzo[ a ]pyrene diol epoxide-DNA cis adduct formation through a trans chlorohydrin intermediateProceedings of the National Academy of Sciences, 1997
- Expanded Analysis of Benzo[a]pyrene−DNA Adducts Formed in Vitro and in Mouse Skin: Their Significance in Tumor InitiationChemical Research in Toxicology, 1996
- Chloride ions catalyze the formation of cis adducts inthe binding of anti-benzo[a]pyrene diol epoxide to nucleicacids.Proceedings of the National Academy of Sciences, 1994
- Halide-Catalyzed cis Product Formation in the Hydrolysis of anti-Benzo[a]pyrene Diol Epoxide and Its Alkylation of Poly(A)Chemical Research in Toxicology, 1994
- Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzymes and relevance to molecular epidemiology.Environmental Health Perspectives, 1992
- Metabolism and cytotoxicity of benzo(a)pyrene in the human lung tumour cell line NCI-H322Xenobiotica, 1988
- Comparison of hydrocarbon - DNA adducts formed in mouse skin in vivo and in organ culture in vitro following treatment with benzo[a]pyreneCarcinogenesis: Integrative Cancer Research, 1986