NONSPECIFIC DESENSITIZATION THERAPY IN ALLERGIC ASTHMA
- 1 December 1925
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 36 (6) , 779-787
- https://doi.org/10.1001/archinte.1925.00120180031004
Abstract
Nonspecific desensitization and nonspecific protein therapy have become recognized factors in immunity. Rosenau and Anderson1have shown that animals receiving repeated injections of foreign proteins become markedly insusceptible to anaphylactic shock. Longcope2writes: "It seems impossible to avoid the conclusion that in animals sensitized to two proteins anaphylactic shock to the one reduces temporarily the sensitiveness to the second." Dale3found that a guinea-pig sensitized to several serums and also to egg white could be desensitized to the serum with egg white. Kolmer,4in referring to nonspecific protein therapy, says that "nonspecific activities of bacterial vaccine may exert beneficial and curative effects in disease to which the bacteria incorporated in the vaccine has no etiologic relationship." CLINICAL REPORTS ON NONSPECIFIC DESENSITIZATION IN ASTHMA Numerous clinical reports are accumulating which show the beneficial effect of various nonspecific desensitizing agents in asthma as well as in hay-fever, and other sensitization conditions. Miller5This publication has 0 references indexed in Scilit: