Gardnerʼs Syndrome

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Abstract
A case of Gardner''s syndrome has been reported in which the presence of intestinal polyposis was suspected on the basis of the patient''s surface features. A study of the patient''s family history, although difficult to compile, revealed a death from cancer in the father and surface lumps in a sibling and 2 of the patient''s 4 children. The literature on Gardner''s syndrome has been reviewed and summarized. Hypotheses as to the mode of inheritance of this syndrome are: a single dominant gene, a variation in penetrance of a single gene or 3 closely linked genes.