Investigating the Function of Ion Channels in Tethered Lipid Membranes by Impedance Spectroscopy
- 1 March 2005
- journal article
- Published by Springer Nature in MRS Bulletin
- Vol. 30 (3) , 207-210
- https://doi.org/10.1557/mrs2005.54
Abstract
The function of biologically important ion channels can be measured in supported lipid membranes by impedance spectroscopy. This approach offers substantial advantages over traditional electrophysiological measurements. In this article, we present an overview of the field, with a special emphasis on the reconstitution of ion channels in lipid bilayers tethered to gold electrodes and the modulation of their channel activity by specific ligand binding.Keywords
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