Insecticide Solvents: Interference with Insecticidal Action
- 10 June 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 196 (4295) , 1211-1213
- https://doi.org/10.1126/science.860135
Abstract
Several commercial solvent mixtures commonly used as insecticide carriers in spray formulations increase by more than threefold the microsomal N-demethylation of p-chloro N-methylaniline in midgut preparations of southern army-worm (Spodoptera eridania) larvae exposed orally to the test solvents. Under laboratory conditions, the same solvent mixtures exhibit a protective action against the in vivo toxicity of the insecticide carbaryl to the larvae. The data are discussed with respect to possible solvent-insecticide interactions occurring under field conditions and, more broadly, to potential toxicological hazards of these solvents to humans.This publication has 16 references indexed in Scilit:
- 10.1007/BF00334311Published by Test accounts ,2011
- Induction of detoxifying enzymes in insectsJournal of Agricultural and Food Chemistry, 1974
- Phenobarbital induction of detoxifying enzymes in resistant and susceptible housefliesPesticide Biochemistry and Physiology, 1973
- Enzyme induction in the housefly: The specificity of the cyclodiene insecticidesPesticide Biochemistry and Physiology, 1972
- Microsomal Drug Metabolizing Enzymes in InsectsDrug Metabolism Reviews, 1972
- Drug enzyme induction and drug interactions: Literature tabulationToxicology and Applied Pharmacology, 1971
- Effects of chlorcyclizine or phenobarbital on in vitro detoxication activity by larval wax moth gut homogenatesToxicology and Applied Pharmacology, 1971
- Metabolism of carbamate insecticide chemicals in plants and insectsJournal of Agricultural and Food Chemistry, 1970
- INDUCTION OF MICROSOMAL OXIDASES BY DIELDRIN IN MUSCA DOMESTICAEntomologia Experimentalis et Applicata, 1970
- Microsomal mixed-function oxidases in insects—IBiochemical Pharmacology, 1969