Reductive O‐ and N‐alkylations. Alternative catalytic methods to nucleophilic substitution
- 1 January 1996
- journal article
- research article
- Published by Wiley in Recueil des Travaux Chimiques des Pays-Bas
- Vol. 115 (4) , 231-238
- https://doi.org/10.1002/recl.19961150408
Abstract
Different amides have been selectively mono‐N‐alkylated using catalytic heterogeneous palladium and carbonyl compounds as alkylating agents. The same salt free method has been applied to the synthesis of ethers from alcohols. Reaction parameters have been studied in detail and a mechanism is proposed.Keywords
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