Factors affecting the in vitro activity of cefoperazone against the Bacteroides fragilis group
Open Access
- 1 December 1981
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 20 (6) , 723-725
- https://doi.org/10.1128/aac.20.6.723
Abstract
The in vitro activity of cefoperazone against 32 strains of bacteria of the Bacteroides fragilis group was determined on four media by using a variety of test parameters. Lower mean minimal inhibitory concentrations (MICs) were obtained on Mueller-Hinton blood agar and supplemented brain heart infusion agar than were obtained on brucella laked blood agar or Wilkins-Chalgren agar. Higher MICs were obtained with 6-h inocula than with 24-h inocula, and slightly higher MICs were obtained with tests read at 48 as compared with 24 h. Conducting tests in an anaerobic glove box had little effect. The greatest differences in mean MICs were seen with inoculum densities of 10(4) and 10(5) colony-forming units.This publication has 10 references indexed in Scilit:
- In vitro activity of N-formimidoyl thienamycin, moxalactam, and other new beta-lactam agents against Bacteroides fragilis: contribution of beta-lactamase to resistanceAntimicrobial Agents and Chemotherapy, 1981
- Influence of inoculum size on activity of cefoperazone, cefotaxime, moxalactam, piperacillin, and N-formimidoyl thienamycin (MK0787) against Pseudomonas aeruginosaAntimicrobial Agents and Chemotherapy, 1980
- Susceptibilities of anaerobic bacteria to cefoperazone and other antibioticsAntimicrobial Agents and Chemotherapy, 1980
- Cefoperazone (T-1551), a new semisynthetic cephalosporin: comparison with cephalothin and gentamicinAntimicrobial Agents and Chemotherapy, 1980
- Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporinAntimicrobial Agents and Chemotherapy, 1980
- Comparative in vitro activity of 1-oxa-beta-lactam (LY127935) and cefoperazone with other beta-lactam antibiotics against anaerobic bacteriaAntimicrobial Agents and Chemotherapy, 1980
- Susceptibility of anaerobic bacteria to cefoperazone and other beta-lactam antibiotics.1980
- In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporinAntimicrobial Agents and Chemotherapy, 1979
- Comparative Activity and β-Lactamase Stability of Cefoperazone, a Piperazine CephalosporinAntimicrobial Agents and Chemotherapy, 1979
- Susceptibility of Anaerobes to Cefoxitin and Other CephalosporinsAntimicrobial Agents and Chemotherapy, 1975