GASTRIC-ACID AND SERUM GASTRIN SECRETION BEFORE AND AFTER BYPASS OF SMALL-INTESTINE FOR MORBID OBESITY

  • 1 January 1976
    • journal article
    • research article
    • Vol. 142  (4) , 521-523
Abstract
Six obese patients undergoing end-to-side jejunoileal bypass had gastric acid output and serum gastrin measurements performed preoperatively and within 3 mo. postoperatively. Meat extract stimulated acid output was higher in obese than in normal patients. Following the bypass procedure, basal and meat extract stimulated acid output significantly decreased. Basal and meat extract stimulated serum gastrin levels did not change following bypass. After a small intestinal bypass, acid output decreases. Gastrin plays no role in this change.

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