Thiol–Protein Disulfide Oxidoreductase Activity in Human Placental Tissue Homogenates
- 1 May 1972
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry
- Vol. 50 (5) , 507-509
- https://doi.org/10.1139/o72-069
Abstract
Thiol–protein disulfide oxidoreductase activity was detected in the soluble cell fraction of human placental tissue homogenized in sucrose. This activity was demonstrated in the rapid reduction of oxytocin and the somewhat less rapid reduction of insulin by reduced glutathione. The apparent pH optimum of the enzymic activity for the reduction of oxytocin and insulin was found to be near pH 8.Keywords
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