Immunoelectron Microscopic Localization of Fibronectin and Complement to ‘Dense Bodies’ in Bowman’s Capsule and the Glomerular Basement Membrane in Membranous Nephropathy

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Abstract
This study describes dense bodies seen in Bowman's capsule and the glomerular basement membrane in biopsies of membranous glomerulonephritis. Within these bodies, silver-enhanced immunogold labelling demonstrated the presence of fibronectin and the complement component C3b. These results suggests that dense bodies may play a role in opsonization and the immune process in membranous glomerulonephritis.

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