Brainstem seizures in hydranencephaly

Publisher Website
Google Scholar
Abstract
Article abstract A child with hydranencephaly had seizures typical for the neonatal period, including frequent clonic episodes and a paroxysmal electroencephalogram (EEG) with spikes, and at postmortem had no brain above the mesencepha-lon except for an unconnected hippocampal remnant. Seizures of several types and flattened or rarely paroxysmal EEGs have been described in hydranencephaly, but in none did autopsy show as incomplete a central nervous system as in the present case. Epileptic foci and neonatal seizures indistinguishable from those in which brain formation is normal may occur at a brainstem level when telencephalon and diencephalon are absent. Dener-vation and aberrant regeneration are possible epileptogenic mechanisms in the immature brain stem of this child.

This publication has 0 references indexed in Scilit: