Monte Carlo Studies of Selection and Inbreeding in Swine. II. Inbreeding Coefficients

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Abstract
Originally, Wright (1921, 1922) proposed the quantity, F, as an inbreeding coefficient indicating “the departure from the amount of homozygosis under random mating to complete homozygosis.” F has since been used as a measure of such departure relative to a specified foundation stock, not necessarily random-bred (Wright, 1951). The most important inbreeding coefficient (Wright, 1951, 1955) and the one of concern here is the F-value pertaining to neutral autosomal disomic loei. In the strictest sense, F measures the changes in homozygosis (or, homozygosity) due only to parental relationship. Malecot (1948) showed that these changes in homozygosity also can be expressed in terms of probability. In biological populations, “true” F usually is indeterminable. The inbreeding coefficient, Fp, here, computed from parental relationships, commonly is used as an estimate of F (Wright, 1922; Lush, 1948). More information is needed on its correspondence with the actual state of homozygosity of an individual or population, particularly as it is affected by type of gene action and selection practices. Copyright © 1970. American Society of Animal Science. Copyright 1970 by American Society of Animal Science

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