THE TOXICITY OF HUMAN SERUM FOR THE GUINEA PIG

Open Access
Publisher Website
Google Scholar
Abstract
Toxicity in all fresh human serum for guinea pigs tends to disappear after 48 hrs. after bleeding, and its manifestations are strikingly similar to those of the hetero-philic antibody in immune rabbit serum. An increased toxicity in the serum of antiserum-treated human cases is usually coexistent with production of other antibodies; it tends likewise to disappear in time, after treatment; differential absorption exps. indicated that its character is heterophilic, and its manifestations differ from those of anaphylaxis in that certain circulatory effects[long dash]hemorrhage and increased edema in the lungs and distension of the right heart[long dash]are added to the usual findings in true anaphylactic deaths.

This publication has 1 reference indexed in Scilit: